Responsibilities:

• Formulate medicinal chemistry strategies and utilize the Genesis platform to execute drug discovery programs from Hit ID through candidate nomination.
• Use SBDD principles, optimize physiochemical properties, interpret in vitro and in vivo ADME/PK/Toxicology data, and understand in vitro and in vivo biology data to drive programs.
• Use data visualization software and metric based analysis to form medicinal chemistry hypothesis and prioritize strategies.
• Work with other drug discovery disciplines (biology, DMPK, software engineers, computational chemists) to drive hypothesis driven decisions, improve the platform and contribute to the scientific excellence of the company.
• Communicate and engage regularly with project team members and management.
• Manage a team of CRO chemists anywhere in size from 5-20.
• Mentor internal chemists as well as other scientific disciplines on medicinal chemistry principles.

Education and Experience Requirements:

• PhD in synthetic organic chemistry or medicinal chemistry with at least 8 years of industrial drug discovery experience OR
• MS in synthetic organic chemistry with at least 14 years of industrial drug discovery experience.

Skills and Knowledge Required:

• Expert medicinal chemistry knowledge with SBDD and physical property-based optimization of drug-like space.
• Expert and metric-based and data visualization to drive prioritization and efficiency.
• Expert synthetic chemistry knowledge and problem-solving skills.
• Ability to manage external CRO chemistry resources effectively.
• Strong communication skills, both in informal team settings as well as professional presentations.
• Motivated team player with strong critical thinking skills, a high degree of independence, strong creative problem-solving skills and ability to adapt to project changes.

What we Offer:

• We offer a competitive salary & equity
• Excellent medical, dental and vision coverage (Genesis pays 100% of premiums for employees)
• Free lunches (and dinner if needed) in the office, along with fully stacked kitchen with snacks
• Work closely with a team on the cutting edge of AI research
• Open, flexible PTO
• 401K Plan